IgG4-Related Disease: Symptoms, Causes, Diagnosis, and Modern Treatment Options
Introduction IgG4-related disease (IgG4-RD) is a long-term immune-mediated condition in which an abnormal immune response leads to inflammation, tissue enlargement, and progressive scarring (fibrosis) in one or more organs. The disease is driven by immune cells producing excessive amounts of immunoglobulin G4 (IgG4),